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CCNK Polyclonal Antibody, 100ul Supplements Alternate splicing results in multiple

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CCNK Polyclonal Antibody, 100ul Supplements Alternate splicing results in multipleThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

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Description

Alternate splicing results in multiple transcript variants encoding distinct isoforms

The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form

suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation

head and neck cancers

Contributes to cell motility by controlling actin dynamics

CCNK Polyclonal Antibody, 100ul Supplements Alternate splicing results in multipleThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

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