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JAMA 333 , 113114 (2025)

Increased Interleukin-23 is Associated With Increased Disease Activity in Patients With Rheumatoid Arthritis

A systematic review published in a 2025 orthopedic sports medicine journal, covering 35 preclinical studies, confirmed that BPC-157 reduced inflammatory cytokines and improved muscle injury outcomes

Once the initial phase is complete, most patients transition to a maintenance plan that ranges from once every one to two weeks, or sometimes monthly, depending on individual response and wellness goals

However, prospective controlled trials on large samples are needed to confirm these preliminary data