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Ref-1 (Acetyl Lys7) Polyclonal Antibody, 50ul Serum The beta subunit may assist

SKU: 58086684678

4.3
USD162.00 USD191.00

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Ref-1 (Acetyl Lys7) Polyclonal Antibody, 50ul Serum The beta subunit may assistApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

The beta subunit may assist in binding of the phospholipid substrate (Probable)

This may be accomplished through interaction with p21-activated kinase

which is composed of 13 subunits: EIF3A

This protein exhibits mitogenic activity for keratinizing epidermal cells

reduces the transcriptional activity of C/EBPδ

Ref-1 (Acetyl Lys7) Polyclonal Antibody, 50ul Serum The beta subunit may assistApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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