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Nonwounded skin showed a network of elastic fibers in the papillary dermis, but scar tissue either showed thin and separate elastic fibers, thick elastin deposits, or even a lack of elastic fibers

Such an indication is unique from most other drugs and compounds identified by the NIA-supported Intervention Testing Program (ITP) to improve lifespan, as acarbose, 17--estradiol, nondihydroguaiaretic acid (NDGA), and protandim, all preferentially improve male lifespan 35,36

Although the field of ferroptosis remains in its infancy, several promising targets and treatment approaches have already been identified