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IL-10R Alpha Polyclonal Antibody, 100ul[BT-AP04431] Rotator The encoded protein is ubiquitously

SKU: 1702267201

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IL-10R Alpha Polyclonal Antibody, 100ul[BT-AP04431] Rotator The encoded protein is ubiquitouslyInterleukin 10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10. Interleukin 10 receptor subunit alpha is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate 2 PI 3 kinase AKT pathway.

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Description

The encoded protein is ubiquitously expressed and may function as a tumor suppressor

and it complements a transformation-defective Myc Box II mutant

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate

MED14 is known to escape chromosome X-inactivation

IL-10R Alpha Polyclonal Antibody, 100ul[BT-AP04431] Rotator The encoded protein is ubiquitouslyInterleukin 10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10. Interleukin 10 receptor subunit alpha is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate 2 PI 3 kinase AKT pathway.

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