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TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 100ul Culture Tubes NFKB1 appears to have dual

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TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 100ul Culture Tubes NFKB1 appears to have dualThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors and forms a heterodimeric complex with TRAF1. This protein is required for TNF alpha mediated activation of MAPK8 JNK and NF kappaB. The protein complex formed by this protein and TRAF1

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Description

NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)

but may also be involved in the development of atherosclerosis

This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis

resulting in members with and without DNA-binding properties

TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 100ul Culture Tubes NFKB1 appears to have dualThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors and forms a heterodimeric complex with TRAF1. This protein is required for TNF alpha mediated activation of MAPK8 JNK and NF kappaB. The protein complex formed by this protein and TRAF1

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