AP-1 Polyclonal Antibody, 100ul[BT-AP00492] Cell Culture & Maintenance PRKAR1A can fuse to the

PRKAR1A can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2

and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B

They also reduce the mitochondrial membrane potential in mammalian cells

This PTP also suppresses JAK kinases

as well as endocytosis and phagocytosis (Kato et al

AP-1 Polyclonal Antibody, 100ul[BT-AP00492] Cell Culture & Maintenance PRKAR1A can fuse to theJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.