CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette It was also found to

It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues

Activated by diacylglycerol (DAG) (By similarity)

and can bind RNA

This gene encodes a homeodomain-containing protein that plays a role in eye development

Disruption of this gene has been implicated in Carpenter syndrome as well as cancer

CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette It was also found toCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.