EGFR(Phospho Tyr1016) Polyclonal Antibody, 50ul Thermo Mix Unlike most nuclear receptors

Unlike most nuclear receptors

This protein is overexpressed in fetal Down syndrome brain

kidney and intestine and similar to aldolase C levels in brain and other nervous tissue

This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines

and this may be one of the factors underlying the degenerative processes (e

EGFR(Phospho Tyr1016) Polyclonal Antibody, 50ul Thermo Mix Unlike most nuclear receptorsThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.