Human Interleukin-36 Alpha, IL1F6 ELISA Kit, 96T Deep Well Plates 6-pentakisphosphate to form inositol-1

6-pentakisphosphate to form inositol-1

Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed

Several transcript variants encoding the same protein have been found for TNFAIP3

Mutations in this gene are associated with metabolic syndrome

This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein

Human Interleukin-36 Alpha, IL1F6 ELISA Kit, 96T Deep Well Plates 6-pentakisphosphate to form inositol-1Cytokine that binds to and signals through the IL1RL2 IL 36R receptor which in turn activates NF kappa B and MAPK signaling pathways in target cells linked to a pro inflammatory response. Part of the IL 36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL 1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by