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PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 100ul Nucleic Acid Amplification The protein encoded by this

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PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 100ul Nucleic Acid Amplification The protein encoded by thisThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange

The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter

and fungi so that they can be neutralized by phagocytic engulfment

Two alternately spliced transcript variants of MAPKAPK5 encoding distinct isoforms have been reported

Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase

PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 100ul Nucleic Acid Amplification The protein encoded by thisThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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