GSAML Polyclonal Antibody, 20ul Plates & Dishes Acyl-coenzyme A thioesterase 4 is

Acyl-coenzyme A thioesterase 4 is an enzyme encoded by the ACOT4 gene in humans and is mapped to chromosome 14

The protein encoded by this gene is an enzyme| which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway

The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis

This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M

Among its related pathways are Hematopoietic cell lineage and B Cell Development Pathways

GSAML Polyclonal Antibody, 20ul Plates & Dishes Acyl-coenzyme A thioesterase 4 isThis gene encodes a protein thought to be a signaling molecule associated with germinal centers, the sites of proliferation and differentiation of mature B lymphocytes. Alternate splicing results in multiple transcript variants.