CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds

Mutations in this gene have been linked to severe spermatogenic failure and infertility in males

Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene

Three alternatively spliced variants encoding different isoforms have been described for this gene

and a short C-terminal extracellular region

CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes Peptidyl-prolyl cis/trans isomerases (PPIases) catalyzeDDIT3 encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. DNA damage inducible transcript 3 functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.