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ERAP1 Polyclonal Antibody, 100ul Protein Expression Belongs to the RAB6IP1 family

SKU: 37814558049

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ERAP1 Polyclonal Antibody, 100ul Protein Expression Belongs to the RAB6IP1 familyEndoplasmic reticulum aminopeptidase 1 encoded by ERAP1 is an aminopeptidase involved in trimming HLA class I binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for ERAP1.

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Description

Belongs to the RAB6IP1 family

May be involved in Rab6-mediated GTPase signaling

A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes

therapeutic drugs

EPS8L1 encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8)

ERAP1 Polyclonal Antibody, 100ul Protein Expression Belongs to the RAB6IP1 familyEndoplasmic reticulum aminopeptidase 1 encoded by ERAP1 is an aminopeptidase involved in trimming HLA class I binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for ERAP1.

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