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Neither agent has received MHRA marketing authorisation for the indications most commonly sought, and no formal interaction data exist for this combination

If pregnancy is a possibility, contraception must be reliable, and note that tirzepatide may reduce the effectiveness of oral contraceptives through delayed gastric emptying

Before taking semaglutide while breastfeeding, discuss the risks and benefits with your healthcare provider

Working with a registered dietician can have added benefits for those women struggling with low breastmilk supply, as there are numerous dietary interventions that may help with increasing breastmilk production

The approved injection sites for most GLP-1 medications include the abdomen (stomach area), thigh, and upper arm