ADCY5 Rabbit Polyclonal Antibody, 50ul Centrifugal Filter The enzyme is responsible for

The enzyme is responsible for the synthesis of histidyl-transfer RNA

which can cause excessive production of reactive oxygen species and cell stress

The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1

An important paralog of this gene is RNF214

This PTP is expressed primarily in hematopoietic cells| and functions as an important regulator of multiple signaling pathways in hematopoietic cells

ADCY5 Rabbit Polyclonal Antibody, 50ul Centrifugal Filter The enzyme is responsible forThis gene encodes a member of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2