Ku-80 (Acetyl Lys565) Polyclonal Antibody, 50ul 3D Cell Culture Consumables Multiple translation initiation codons and

Multiple translation initiation codons and alternative splicing result in many different isoforms being translated

bringing newly synthesized histones H3 and H4 to replicating DNA

A germline mutation of VHL is the basis of familial inheritance of VHL syndrome

and specifically binds to intronic polypyrimidine tracts

Mutations in this gene have been reported to be associated with nonsyndromic hearing loss

Ku-80 (Acetyl Lys565) Polyclonal Antibody, 50ul 3D Cell Culture Consumables Multiple translation initiation codons andThe protein encoded by this gene is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events. This gene functionally