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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture It heterodimerizes with asparagine-linked glycosylation

SKU: 49318005994

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture It heterodimerizes with asparagine-linked glycosylationBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation

Diseases associated with GLB1L3 include leber congenital amaurosis

Made from durable PS material

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture It heterodimerizes with asparagine-linked glycosylationBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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