MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes This protein has been shown

This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation

Isoform 1 is involved in UBTF-activated transcription

one C-terminal RRM domain

Some of these isoforms are beta subunits

MDM2(Phospho Ser166) Polyclonal Antibody, 20ul Metabolic enzymes This protein has been shownThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript