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Bcl-6 Polyclonal Antibody, 50ul[BT-AP00866] Cell Culture Dishes but not rodents

SKU: 52432569746

4.4
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Bcl-6 Polyclonal Antibody, 50ul[BT-AP00866] Cell Culture Dishes but not rodentsThe protein encoded by BCL6 (B cell CLL lymphoma 6) is a zinc finger transcription factor and contains an N terminal POZ domain. This protein acts as a sequence specific repressor of transcription, and has been shown to modulate the transcription of STAT dependent IL 4 responses of B cells. This protein can interact with a variety of POZ containing proteins that function as transcription corepressors. BCL6 is found to be frequently translocated and

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Description

but not rodents

The encoded protein is expressed in lens fiber cells after differentiation has begun

The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope

Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein

enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

Bcl-6 Polyclonal Antibody, 50ul[BT-AP00866] Cell Culture Dishes but not rodentsThe protein encoded by BCL6 (B cell CLL lymphoma 6) is a zinc finger transcription factor and contains an N terminal POZ domain. This protein acts as a sequence specific repressor of transcription, and has been shown to modulate the transcription of STAT dependent IL 4 responses of B cells. This protein can interact with a variety of POZ containing proteins that function as transcription corepressors. BCL6 is found to be frequently translocated and

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