MC2-R Polyclonal Antibody, 50ul Drug Development and Evaluation This encoded protein is characterized

This encoded protein is characterized by two WW domains

Unlike the other two isoforms

This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain

BRE is upregulated in several types of cancer

contains one exonuclease domain and one SAP domain

MC2-R Polyclonal Antibody, 50ul Drug Development and Evaluation This encoded protein is characterizedMC2R encodes one member of the five member G protein associated melanocortin receptor family. Melanocortins (melanocyte stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.