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BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos a transmembrane segment

SKU: 5771205827

4.8
USD162.00 USD210.00

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos a transmembrane segmentBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

a transmembrane segment

is associated with mutations in the ABCA12 gene

with biallelic

this protein is sometimes secreted

Multiple alternatively spliced transcript variants encoding the same protein are observed

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos a transmembrane segmentBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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