DNA pol Epsilon 4 Polyclonal Antibody, 50ul Organelle Studies This protein plays a role

This protein plays a role in several cellular processes

lack of a negative regulatory phosphorylation site

indicating that the encoded protein might also represent a transcription factor

a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53

The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB)

DNA pol Epsilon 4 Polyclonal Antibody, 50ul Organelle Studies This protein plays a rolePOLE4 is a histone fold protein that interacts with other histone fold proteins to bind DNA in a sequence independent manner. These histone fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.