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JAK2(Phospho Tyr221) Polyclonal Antibody, 100ul CellSafe™ Activity of this protein is

SKU: 60922983129

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JAK2(Phospho Tyr221) Polyclonal Antibody, 100ul CellSafe™ Activity of this protein isThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

Activity of this protein is key in the development of neural tissues| particularly the eye

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides

An important paralog of this gene is R3HCC1

also known as the tetraspanin family

Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis

JAK2(Phospho Tyr221) Polyclonal Antibody, 100ul CellSafe™ Activity of this protein isThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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