PTN14 Polyclonal Antibody, 20ul Cell Screening and Imaging Members of arrestin/beta-arrestin protein family

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones| neurotransmitters| or sensory signals

This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia

and an intracellular kinase domain

tissue remodeling

This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress

PTN14 Polyclonal Antibody, 20ul Cell Screening and Imaging Members of arrestin/beta-arrestin protein familyThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N terminal noncatalytic domain similar to that of band 4. 1 superfamily cytoskeleton associated proteins, which suggested the membrane or cytoskeleton localization of