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ASPM Polyclonal Antibody, 100ul Site-directed Mutagenesis May play a role in

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ASPM Polyclonal Antibody, 100ul Site-directed Mutagenesis May play a role inThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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Description

May play a role in all aspects of hemoglobin production: globin synthesis| heme synthesis| and the procurement of iron

Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1)

hemokine CC receptors (CCRs) predominantly recognize CC chemokines

growth regulation

Aberrant expression of this gene is associated with prostate tumor progression

ASPM Polyclonal Antibody, 100ul Site-directed Mutagenesis May play a role inThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found

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