Tryptase-3 Polyclonal Antibody, 50ul Thermal Control Increased transcriptional expression of POT1

Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression

the homodimer may act as a repressor of transcription

This gene is the human ortholog of mouse Tbx21/Tbet gene

Involved in TGFbeta-mediated mesoderm induction

but in contrast to other family members

Tryptase-3 Polyclonal Antibody, 50ul Thermal Control Increased transcriptional expression of POT1Tryptases comprise a family of trypsin like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13. 3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which