ARHGAP23 Polyclonal Antibody, 50ul Micro Centrifuge Tubes The TRRAP/TIP60 complex acetylates nucleosomal

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

Co-transcription of this gene with adjacent genes has been observed

The encoded protein functions as either a homodimer or as a heterodimer with similar family members

Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease

The gene is specific to the primate lineage

ARHGAP23 Polyclonal Antibody, 50ul Micro Centrifuge Tubes The TRRAP/TIP60 complex acetylates nucleosomalThe RHO family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP bound form and active in the GTP bound form. GTPase activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP.