TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis The nuclear prelamin A recognition

The nuclear prelamin A recognition factor encoded by NARF binds to the prenylated prelamin A carboxyl-terminal tail domain

and a widespread distribution in the brain

Contains 2 PLD phosphodiesterase domains

Defects in this gene lead to many pathophysiologic problems

often at the N- or C-terminus of the protein

TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis The nuclear prelamin A recognitionTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.