SNX13 Rabbit Polyclonal Antibody, 20ul Insect Expression 3'|5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze

3'|5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling

A similar protein in mouse plays a role in gametogenesis in both sexes

Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein| which is thought to be involved in the process of blocking IFN-alpha response by adenovirus

The enzyme forms a homotetramer that is localized to the lysosome

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SNX13 Rabbit Polyclonal Antibody, 20ul Insect Expression 3'|5'-cyclic nucleotide phosphodiesterases (PDEs) catalyzeThis gene encodes a PHOX domain and RGS domain containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this