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The approval followed the landmark SURPASS trial series, in which tirzepatide consistently outperformed placebo and other diabetes medications in reducing HbA1c and body weight

To minimize bruising, patients should follow the manufacturer's Instructions for Use, apply gentle pressure after injection without rubbing the site, and avoid injecting into bruised, scarred, or irritated areas

Orally disintegrating tablets (ODTs) and sublingual drops are additional formats being explored, each with their own dosing systems that bypass the unit measurement confusion entirely

If the medication was left at room temperature for a single night, it may still be safe to use, but its total shelf life could be reduced

The cost of compounded tirzepatide may differ from that of FDA-approved alternatives, and it is important to consider this when evaluating treatment options