S4A7 Polyclonal Antibody, 50ul Human Genome Knockout Libraries A chromosomal translocation including this

A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers

This gene encodes a cytokine-like protein

SFTPB encodes the pulmonary-associated surfactant protein B (SPB)

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This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias

S4A7 Polyclonal Antibody, 50ul Human Genome Knockout Libraries A chromosomal translocation including thisThis locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1: 1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.