Rad18(Phospho-Ser403) Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) frizzled class receptor)is a G

frizzled class receptor)is a G protein-coupled receptor that interacts with the patched protein

MIM 600682) and MCT2 (SLC16A7

Mutations in ITCH are a cause of syndromic multisystem autoimmune disease

which is responsible for pituitary development and hormone expression

Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes

Rad18(Phospho-Ser403) Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) frizzled class receptor)is a GThe protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6 which is an ubiquitin conjugating enzyme required for post replication repair of damaged DNA. Similar to its yeast counterpart this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring finger motif. Mutation of this motif results in defective