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5A-1MQ-treated mice switched from WD to LD were particularly distinct from mice in the other groups when k-means clustering was applied to the ASV relative abundance data

The safety was preliminarily verified: The acute toxicity test showed that a single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice

in total, 9 genera (including the unclassified group) and 38 metabolites met these criteria (metabolites published in Sampson et al., 2021 13 )