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FAM111B Polyclonal Antibody, 50ul sgRNA Library Construction Deficiency of this protein is

FAM111B Polyclonal Antibody, 50ul sgRNA Library Construction Deficiency of this protein is

Name: FAM111B Polyclonal Antibody, 50ul sgRNA Library Construction Deficiency of this protein is
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FAM111B Polyclonal Antibody, 50ul sgRNA Library Construction Deficiency of this protein isFAM111B encodes a protein with a trypsin like cysteine serine peptidase domain in the C terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog

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Description

Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE)

subunit:Interacts with CENPA (via CATD domain)

CENPB (MIM 117140)

Each of these proteins

An important paralog of this gene is DNAL4

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