AES Polyclonal Antibody, 20ul Cell Biology MOB kinase activator 1B encoded

MOB kinase activator 1B encoded by MOB1B is similar to the yeast Mob1 protein

The use of alternate polyadenylation sites has been found for this gene

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family

The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4

This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

AES Polyclonal Antibody, 20ul Cell Biology MOB kinase activator 1B encodedThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms