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IκB-alpha Polyclonal Antibody, 20ul[BT-AP10545] Sample Library Tubes this process requires Fas-mediated dephosphorylation

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IκB-alpha Polyclonal Antibody, 20ul[BT-AP10545] Sample Library Tubes this process requires Fas-mediated dephosphorylationThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

this process requires Fas-mediated dephosphorylation of Max

Osteoporosis is characterized by reduced bone mineral density| disrutption of bone microarchitecture| and the alteration of the amount and variety of non-collagenous proteins in bone

The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface

Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos

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IκB-alpha Polyclonal Antibody, 20ul[BT-AP10545] Sample Library Tubes this process requires Fas-mediated dephosphorylationThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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