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Rac GAP1(Phospho Ser387) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification the level of this protein

SKU: 9517155348

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Rac GAP1(Phospho Ser387) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification the level of this proteinThis gene encodes a GTPase activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on

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Description

the level of this protein in plasma increases greatly during acute phase response to tissue injury

Constitutive activation of this gene caused either by somatic mutations| or genomic duplications of regions that include this gene| have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome

Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype

Chromobox protein homolog 5 is enriched in the heterochromatin and associated with centromeres

A pseudogene of HORMAD1 is located on the long arm of chromosome 6

Rac GAP1(Phospho Ser387) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification the level of this proteinThis gene encodes a GTPase activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on

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