IP3R-I Polyclonal Antibody, 50ul[BT-AP04603] Cryogenic Vials thereby acting as a coactivator
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IP3R-I Polyclonal Antibody, 50ul[BT-AP04603] Cryogenic Vials thereby acting as a coactivatorITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.
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