CNNM4 Rabbit Polyclonal Antibody, 50ul Primary Antibodies MutS beta initiates mismatch repair

MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer

Additional isoforms produced by alternative splicing seem to exist

Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity

Two transcript variants encoding different isoforms have been found for CCNC

AT-rich interactive domain 1 (JARID1) histone demethylase protein family

CNNM4 Rabbit Polyclonal Antibody, 50ul Primary Antibodies MutS beta initiates mismatch repairThis gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone rod dystrophy and amelogenesis imperfecta.