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The resulting accumulation of fat in hepatocytes makes the liver susceptible to inflammatory mediators and/or toxic agents, leading to progressive injury, which progresses to alcoholic steatohepatitis (ASH), fibrosis, cirrhosis, and cancer (Li et al., 2024

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The study was a randomized, double-blind, parallel, placebo-controlled trial with 24 obese males aged 19-49 years in two groups: MK-677 (25 mg/day

One example is Insulin Autoimmune Syndrome (IAS), in which spontaneous hypoglycemia occurs due to the presence of insulin autoantibodies triggered by exogenous insulin [83]