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doi: 10.3389/fcimb.2017.00110 154 NelsonA

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Decades of research in the field confirmed that a striking number of genes associated with familial PD are directly or indirectly involved in the regulation of mitochondrial function, including PINK1, Parkin, DJ-1, leucine-rich repeat kinase 2 (LRRK2), -syn, ubiquitin carboxyl-terminal hydrolase ligase-1 (UCHL-1), nuclear receptor-related 1 (NURR1), vacuolar protein sorting 13 C (VPS13 C), and high-temperature demand protein A2 (HTRA2) [125,126,127]

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