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[9] Cimetidine has been shown in controlled studies to reduce lidocaine clearance by approximately one-third after only 24 hours of co-administration, leading to higher steady-state concentrations

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, Vidovic, T

We previously identified a direct protein-protein interaction between DAT and dopamine D2 receptor (D2R) [23], and this interaction is mediated through the first 15 amino acids (i.e