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this definition of CB has been predictive of more severe symptoms and high-risk patient groups [11]

We have indicated that male mice could also successfully establish NTG induced CM model [17, 18], it is well known that sex differences in migraine is mainly due to the role of estrogen [44, 45], thus, to avoid the influence of estrogen, we selected male mice for further study

Hinwood AL, Callan AC, Ramalingam M, et al

He described the therapy as probably just the beginning of a new generation of engineered therapeutics in the metabolic segment. Speaking about safety concerns, Dr Kovil said the gastrointestinal side effects observed in the trial - including nausea, diarrhea, constipation, and vomiting - are largely similar to those already seen with GLP-1based therapies currently on the market

Definitions of covariates.Table S4