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Rucaparib phosphate - CAS# 459868-92-9 dophyllotoxin ACBI1 can induce anti-proliferative effects

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Rucaparib phosphate - CAS# 459868-92-9 dophyllotoxin ACBI1 can induce anti-proliferative effectsRucaparib is a tricyclic indole poly(ADP Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1 mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. Product information CAS Number: 459868 92 9 Molecular Weight: 421. 36 Formula: C19H21FN3O5P Synonym: AG014699

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Description

ACBI1 can induce anti-proliferative effects and apoptosis

CAS Number: 1421227-52-2

This product has not formal name

It acts by binding to ST (serotonin transporter/SERT) with high affinity

Smiles: CC(C)(C)C1=CC(NC(=O)NC2C=CC(=CC=2)NC(=O)C2=CC=C(C=N2)OC2CC(C)(C)N(CC)C(C)(C)C2)=NO1

Rucaparib phosphate - CAS# 459868-92-9 dophyllotoxin ACBI1 can induce anti-proliferative effectsRucaparib is a tricyclic indole poly(ADP Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Rucaparib selectively binds to PARP1 and inhibits PARP1 mediated DNA repair, thereby enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. Product information CAS Number: 459868 92 9 Molecular Weight: 421. 36 Formula: C19H21FN3O5P Synonym: AG014699

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