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In the normal physiological state (Figure 3a), GSH is produced by the condensation of the amino acids glutamate and cysteine to form the dipeptide -glutamylcysteine, which is catalyzed by the enzyme, -glutamyl cysteine synthetase.The dipeptide then condenses with the amino acid glycine to form the tripeptide GSH which is catalyzed by the enzyme GSH synthetase

(2) Diagnostic potential of GPX3: As an extracellular protein, GPX3 is readily detectable in blood, making it a promising biomarker for diagnosing diseases, assessing disease progression, and informing therapeutic decisions, for conditions such as cancer, IBD, inflammatory diseases, and ALS

GHK-Cu at low concentrations is a powerful attractant for capillary cells that build new blood vessels, and a powerful migration stimulant for macrophages and mast cells that remove damaged cellular debris and secrete proteins important for wound contraction and tissue healing [8-9]

10.1016/j.metabol.2015.01.008 65 IvanisevicT.SewduthR