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Under the conditions of unilateral ureteral obstruction and renal ischemia/reperfusion injury, tubular necroptosis is markedly upregulated, which in turn promotes NOD-like receptor protein 3 (NLRP3) inflammasome activation leading to renal fibrosis

S1I, including neutrophils (CCL28 + CD45 + CD11b + Ly6G + cells), monocytes (CCL28 + CD45 + CD11b + Ly6G - Ly6C + F4/80 - cells), and macrophages (CCL28 + CD45 + CD11b + Ly6G - Ly6C - F4/80 + cells)

Ranasinghe SL, Boyle GM, Fischer K, Potriquet J, Mulvenna JP, McManus DP

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