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Ma K, Li M, Song Y, Mao X, Zhang S, Zhang Y, et al

3.2 Methionine restriction potentiates oxidative stress by impairing tumor cell antioxidant defenses A state of oxidative stress arises when ROS are produced and eliminated at unequal rates, causing harm to cellular components

Remarkably, despite the rapid depletion of mitochondrial cysteine under starved conditions, Fe-S cluster synthesis persisted in support of respiratory function through the onset of ferroptosis

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LTA is either hydrated 4 4 4 to form LTB or it is conjugated to GSH by a GST, leukotriene C synthase, to form leukotriene C