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Cardiac Electrophysiology : In a randomized, placebo-controlled crossover study, 79 healthy subjects were administered a single oral dose of JANUVIA 100 mg, JANUVIA 800 mg (8 times the recommended dose), and placebo

You may need to avoid weight loss medications if you: Have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN2) Have a personal or family history of pancreatitis or gallbladder disease Are allergic to any of the ingredients in the medication Are pregnant or breastfeeding Have a history of eating disorders, substance abuse, addiction , or certain mental health conditions If youre interested in weight loss medications, talk to your healthcare provider

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personal AND family history of MTC and MEN-2 , sleep apnea, T1/T2 diabetes, retinopathy, warfarin use, pancreatitis history, severe depression, fatty liver, CHF and PCOS