Ivacaftor (benzenesulfonate) Size:Solid 2 mg Chemical Name: sodium 2-{[3-methyl-4-(2

Chemical Name: sodium 2-{[3-methyl-4-(2

Kinetics experiments revealed that PF-03716556 has a competitive and reversible mode of action

Solubility: DMSO: ≥ 46 mg/mL

Wautier JL

may down-regulate the phophorylation and activation of Erk1 and Erk2 in the Erk1/Erk2 Mapk signaling pathway

Ivacaftor (benzenesulfonate) Size:Solid 2 mg Chemical Name: sodium 2-{[3-methyl-4-(2VX 770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 45% cases of cystic fibrosis, and is included in a combination drug, lumacaftor ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel